Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment of numerous myeloma. Its synthesis or study is crucial for making sure the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-10-1): A key compound during the synthesis of imatinib, a drug that targets unique varieties of cancer, including chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is vital for optimizing the production method CAS NO. 875573-63-0 and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is employed to take care of breast cancer, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Utilized in the remedy of breast cancer. Numerous intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug helpful in managing cancers including ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the cure of colorectal cancer and small cell lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, that 4-[2-(2-Amino-4 have a variety of purposes, like antiviral Homes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for sort 2 diabetic issues that inhibits the enzyme DPP-four to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of varied gluconic acid derivatives, that happen to be used in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor during the synthesis of canagliflozin, a medication made use of to deal with kind 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).